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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS2
All Species:
60.61
Human Site:
S226
Identified Species:
83.33
UniProt:
P61201
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61201
NP_001137359.1
443
51597
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089276
443
51433
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Dog
Lupus familis
XP_862009
444
51751
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG32
422
47418
G215
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
E
Rat
Rattus norvegicus
P61203
443
51578
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521692
705
77929
S473
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Chicken
Gallus gallus
NP_001026767
443
51677
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Frog
Xenopus laevis
Q6IR75
441
51318
S224
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Zebra Danio
Brachydanio rerio
Q6IQT4
443
51553
S226
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94899
444
51508
S227
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Honey Bee
Apis mellifera
XP_392587
444
51537
S227
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
Nematode Worm
Caenorhab. elegans
O01422
495
56762
H223
E
L
A
T
Q
A
I
H
T
K
S
A
I
P
H
Sea Urchin
Strong. purpuratus
XP_780196
444
51783
S227
E
Q
S
L
Q
I
K
S
A
I
P
H
P
L
I
Poplar Tree
Populus trichocarpa
XP_002330981
439
51362
S222
Q
K
A
L
A
I
K
S
A
I
P
H
P
R
I
Maize
Zea mays
NP_001149870
438
51327
S222
Q
R
A
L
S
I
K
S
A
I
P
H
P
R
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W207
439
51168
S222
H
K
A
L
A
I
K
S
A
I
P
H
P
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI58
490
56940
S229
Q
K
A
L
K
V
R
S
A
V
P
H
P
K
I
Conservation
Percent
Protein Identity:
100
N.A.
98.6
99.3
N.A.
23
100
N.A.
53.9
99.7
98.8
99.3
N.A.
83.7
86.4
57.7
85.5
Protein Similarity:
100
N.A.
98.8
99.3
N.A.
43.1
100
N.A.
57.8
99.7
99.3
100
N.A.
91.4
93.4
72.9
92.1
P-Site Identity:
100
N.A.
100
100
N.A.
6.6
100
N.A.
100
100
100
100
N.A.
100
100
6.6
93.3
P-Site Similarity:
100
N.A.
100
100
N.A.
6.6
100
N.A.
100
100
100
100
N.A.
100
100
13.3
93.3
Percent
Protein Identity:
64.1
64.1
N.A.
60.5
N.A.
45.7
Protein Similarity:
80.1
80.3
N.A.
79
N.A.
65.3
P-Site Identity:
66.6
66.6
N.A.
66.6
N.A.
46.6
P-Site Similarity:
86.6
86.6
N.A.
80
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
30
0
12
6
0
0
89
0
0
12
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
71
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% G
% His:
6
0
0
0
59
0
0
6
0
0
6
89
0
0
6
% H
% Ile:
0
0
0
0
0
83
6
0
6
89
0
0
6
0
89
% I
% Lys:
0
18
0
0
6
0
83
0
0
6
0
0
0
6
0
% K
% Leu:
0
6
6
89
0
0
0
0
0
0
0
0
0
65
0
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
89
0
89
6
0
% P
% Gln:
18
65
0
0
12
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
6
0
0
0
0
6
0
0
0
0
0
0
18
0
% R
% Ser:
0
0
65
0
6
0
6
89
0
0
6
0
0
0
0
% S
% Thr:
0
6
0
6
0
0
0
0
6
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
6
0
0
0
6
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _